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Differential expression of potassium channels in placentas from normal and pathological pregnancies: Targeting of the K ir 2.1 channel to lipid rafts
(2012)
Potassium channels play important physiological roles in human syncytiotrophoblasts (hSTBs) from placenta, an epithelium responsible for maternal-fetal exchange. Basal and apical plasma membranes differ in their lipid and ...
Disturbing Lipid Phase Equilibrium in Model Membrane Induced by Lytic Peptides
(2022-04-01)
Lytic peptides are rich in cationic and hydrophobic residues that form amphipathic α-helix when in contact with lipid bilayers. Evidence showed that they act on the lipidic phase of the cell membranes, inserting into the ...
Structural characterization of phosphatidylglycerol model membranes containing the antibiotic target lipid II molecule: a Raman microspectroscopy study
(John Wiley & Sons Ltd, 2017-02)
Effects induced by the incorporation of lipid II (LII) molecule into phosphatidylglycerol (PG) membranes were studied by Raman microspectroscopy. Spectral behavior of multilayer vesicles in liquid crystalline and gel phases ...
Lipid hydroperoxidation effect on the dynamical evolution of the conductance process in bilayer lipid membranes: A condition toward criticality
(American Chemical Society, 2020-08-04)
Cell membranes are one of the main targets of oxidative processes mediated by reactive oxygen species (ROS). These chemical species interact with unsaturated fatty acids of membrane lipids, triggering an autocatalytic chain ...
Sticholysin I–membrane interaction: An interplay between the presence of sphingomyelin and membrane fluidity
(Elsevier Science, 2014-01)
Sticholysin I (St I) is a pore-forming toxin (PFT) produced by the Caribbean Sea anemone Stichodactyla helianthus belonging to the actinoporin protein family, a unique class of eukaryotic PFT exclusively found in sea ...
Lipid model membranes for drug interaction study
(SpringerNew YorkEUA, 2006)
Lipids at the crossroad of α-synuclein function and dysfunction: Biological and pathological implications
(Frontiers Media S.A., 2019-05-01)
Since its discovery, the study of the biological role ofα-synuclein and its pathologicalimplications has been the subject of increasing interest. The propensity to adoptdifferent conformational states governing its aggregation ...
Chitosan derivatives targeting lipid bilayers: Synthesis, biological activity and interaction with model membranes
(2017-01-01)
The antimicrobial activity of chitosan and derivatives to human and plant pathogens represents a high-valued prospective market. Presently, two low molecular weight derivatives, endowed with hydrophobic and cationic character ...